Dr. Mohammed alsanae is currently working as an assistant professor at Pharmaceutical Chemistry Department, College of Pharmacy, Jouf University, KSA. He has more than 56 research and review articles in the field of pharmaceutical medicinal chemistry, were published in high reputable international journals, and two patents have been published. Dr. Al-Sanea has a number of 56 WoS publications, two international patents and a total of eight local and international research grants had been awarded. In 2020, he won a grant from Saudi MOE to support his current research about breast cancer treatment. 

Educational Qualification

• D.,Biological Chemistry, KIST/UST University, South Korea.
• S., Pharmaceutical Chemistry, Assiut University, Egypt.
• S., Pharmaceutical Science, Mansoura University, Egypt.

Research Interests

The main research interest is to design, synthesize, in silico study and develop anticancer agents with different mechanisms of actions. The three potential and interested oncogenic targets are kinases, histone deacetylases and carbonic anhydrases.

Selected publications:

 Al-Sanea, Mohammad M., Ahmad J. Obaidullah, Mohamed E. Shaker, Garri Chilingaryan, Mohammed M. Alanazi, Nawaf A. Alsaif, Hamad M. Alkahtani, Sultan A. Alsubaie, and Mohamed A. Abdelgawad. "A New CDK2 Inhibitor with 3-Hydrazonoindolin-2-One Scaffold Endowed with Anti-Breast Cancer Activity: Design, Synthesis, Biological Evaluation, and In Silico Insights." Molecules 26, no. 2 (2021): 412.

Al-Sanea, Mohammad M., Lizaveta Gotina, Mamdouh FA Mohamed, Della Grace Thomas Parambi, Hesham AM Gomaa, Bijo Mathew, Bahaa GM Youssif et al. "Design, synthesis and biological evaluation of new HDAC1 and HDAC2 inhibitors endowed with ligustrazine as a novel cap moiety." Drug design, development and therapy 14 (2020): 497.

Selim, Samy, Walid Abuelsoud, Mohammad M. Al-Sanea, and Hamada AbdElgawad. "Elevated CO2 differently suppresses the arsenic oxide nanoparticles-induced stress in C3 (Hordeum vulgare) and C4 (Zea maize) plants via altered homeostasis in metabolites specifically proline and anthocyanin metabolism." Plant Physiology and Biochemistry(2021).

Dr. Samy Selim earned a Bachelor Degree in Science from the Suez Canal University, Egypt in 1993. That year, he became a researcher in Faculty of Science, Suez Canal University; he completed his M.Sc. in Microbiological 1998. He obtained his Ph.D. in Microbiological Risk Assessment and Water Pollution from Suez Canal University, Egypt. He worked as a postdoctoral fellow in many international universities (Department of General and Environmental Microbiology, Pécs University, Hungary - Department of Genomics and Biotechnology, Institute of Molecular Biology, Slovak Republic - Department Genetics and Applied Microbiology, University of Debrecen, Hungary – Department of Biology, Western Washington University, Bellingham, USA). He currently serves as Associate Professor of Microbiology, Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, KSA. From 1998 to the present, Dr. Samy Selim has made over 100 contributions to national and international conferences. Furthermore, he has around 120 scientific publications in indexed journals (H-index = 25, 1766 citations, scholar.google.com/citations) and book chapters. His research work focuses on Environmental Health and Safety (particularly on Hazardous material and waste management by microorganisms and higher plants, Food Safety and Management, Climate Change and Environment, Microbial role in waste disposal, recycling and agriculture, purification and characterization of enzymes with potential industrial and biotechnological applications, protocol optimisation for genetically manipulating microorganisms, gene regulation characterization and design and development of contaminated water and soil bioremediation processes by means of microorganisms).

Selected papers published in refereed journals

- Hamada AbdElgawad, Gaurav Zinta, A. Hamed Badreldin, Samy Selim, Gerrit Beemster, Wael

113705. Hozzein, Mohammed A.M. Wadaan, Han Asard, Walid Abuelsoud (2020). Maize root and shoot show distinct profiles of oxidative stress and antioxidant defense under heavy metal toxicity. Environmental Pollution, 258, 113705. doi.org/10.1016/j.envpol.2019.113705

- Helena Van De Velde, Hamada AbdElgawad, Han Asard, Gerrit T. S. Beemster, Samy Selim, Ivan Nijs, Dries Bonte (2019). Interspecific plant competition mediates impact of climate change on the ecophysiology of a plant-herbivore interaction. Functional Ecology; 33:1842– 1853. doi.org/10.1111/1365-2435.13415

- Ahmed M. Saleh, Yasser M. Hassan, Samy Selim, Hamada AbdElgawad (2019). NiOnanoparticles induce reduced phytotoxic hazards in wheat (Triticum aestivumL.) grown under future climate CO2. Chemosphere, Volume 220 ,1047-1057 doi.org/10.1016/j.chemosphere.2019.01.023

- Alexandra de Sousa, Ahmed M. Saleh,TalaatH.Habeeb,YasserM.Hassan , Rafat Zrieq, Mohammed A.M. Wadaanf, Wael N. Hozzein, Samy Selim, Manuela Matos, Hamada AbdElgawad (2019). Silicon dioxide nanoparticles ameliorate the phytotoxic hazards of aluminum in maize grown on acidic soil. Science of the Total Environment 693 (2019) 133636. doi.org/10.1016/j.scitotenv.2019.133636

- Seham M. Hamed, Sherif H. Hassan, Samy Selim, Amit Kumar, Sameh M.H. Khalaf, Mohammed A.M. Wadaan, Wael N. Hozzein, Hamada AbdElgawad (2019). Physiological and biochemical responses to aluminum-induced oxidative stress in two cyanobacterial species. Environmental Pollution 251, 961-969. doi.org/10.1016/j.envpol.2019.05.036

- Seham M. Hamed, Sherif H. Hassan, Samy Selim, Amit Kumar, Sameh M.H. Khalaf, Mohammed A.M. Wadaan, Wael N. Hozzein, Hamada AbdElgawad (2019). Differential responses of two cyanobacterial species to R-metalaxyl toxicity: growth, photosynthesis and antioxidant analyses. Environmental Pollution, 1-20. doi.org/10.1016/j.envpol.2019.113681

- Samy Selim, Yasser M. Hassan, Ahmed M. Saleh, Talaat H. Habeeb, Hamada AbdElgawad (2019). Actinobacterium isolated from a semi-arid environment improves the drought tolerance in maize (Zea maysL.). Plant Physiology and Biochemistry 142, 15–21. doi.org/10.1016/j.plaphy.2019.06.029

- Soad Al Jaouni, Samy Selim, Sherif H. Hassan, Hussein S. H. Mohamad, Mohammed A. M. Wadaan, Wael N. Hozzein, Han Asard and Hamada AbdElgawad (2019). Vermicompost Supply Modifies Chemical Composition and Improves Nutritive and Medicinal Properties of Date Palm Fruits from Saudi Arabia. Frontiers in Plant Science, 10 (Article 424), 1-13.