كلية الصيدلة

الابحاث العلمية بالسنة الميلادية

2016

All-trans retinoic acid potentiates cisplatin-induced kidney injury in rats: impact of retinoic acid signaling pathway (2016) AM Elsayed, TM Abdelghany, ES Akool, AAH Abdel-Aziz,  Mohamed S Abdel-Bakky Naunyn-Schmiedeberg's archives of pharmacology, 1-11


Synthesis of new 7-benzothiazol-2-yl quinolone derivatives as antitumor agents (2016) SA Hussein, H Abd El Maksoud,  KA Moustafa, MM Afify, MS Abdel-Bakky,    Mohamed A. Abdelgawad. Journal of chemical and pharmaceutical research, 8.


Synthesis and cytotoxic activity of acridine derivatives substituted with benzimidazole, benzoxazole and benzothiazole Manal M. Kandeel , Sameeha M. Ali , Mohamed A. Abdelgawad , MS Abdel-Bakky,  Fatma E. A. Mohamed::  Der Pharma Chemica.  8, (2016).


Synthesis, Anticancer Activity, Effect on Cell Cycle Profile, and Apoptosis-Inducing Ability of Novel Hexahydrocyclooctathieno [2, 3-d] pyrimidine Derivatives (2016) AE Kassab, EM Gedawy, AA El-Malah, TM Abdelghany, MS Abdel-Bakky Chemical and Pharmaceutical Bulletin 64 (5), 490-496.


Phytochemical and Pharmacological Evaluations of Ethanolic Extract of Bassia eriophora (2016) A Musa, NS. Al-muaikel and Mohamed S. Abdel-Bakky Der Pharma Chemica  8(12):169-178


Thymoquinone mitigate ischemia-reperfusion-induced liver injury in rats: a pivotal role of nitric oxide signaling pathway (2016) M Abd-Elbaset, ESA Arafa, GA El Sherbiny, MS Abdel-Bakky, Naunyn-Schmiedeberg's Archives of Pharmacology, 1-8

 

2015
  1. All-trans retinoic acid mitigates methotrexate-induced liver injury in rats; relevance of retinoic acid signaling pathway (2015)  MG Ewees, TM Abdelghany, AAH Abdel-Aziz, MS Abdel-Bakky Naunyn-Schmiedeberg's archives of pharmacology, 1-8
  1. Glutamyl cysteine dipeptide suppresses ferritin expression and alleviates liver injury in iron-overload rat model (2015) SA Salama, MS Al-Harbi, MS Abdel-Bakky, HA Omar Biochimie 115, 203-211
  1. Quercetin modulates iNOS, eNOS and NOSTRIN expressions and attenuates oxidative stress in warm hepatic ischemia-reperfusion injury in rats (2015) M Abd-Elbaset, ESA Arafa, GA El Sherbiny, MS Abdel-Bakky. Beni-Suef University Journal of Basic and Applied Sciences.
  1. Carbon tetrachloride-induced liver injury in mice is tissue factor dependent (2015) MS Abdel-Bakky, GK Helal, EM El-Sayed, AS Saad Environmental toxicology and pharmacology 39 (3), 1199-1205
  1. Pioglitazone attenuates diabetes-induced neurodegeneration in parkinsonian rat model (2015) Ahmed R. Mohammed, Mona M. El-Naa, MS. Abdel-Bakky, Ahmed M. Mansour, Gouda K. Helal AlAzhar journal of pharmaceutical science.
  2. The Barrier Properties of Alternative Skin Models for Human Skin Scholars' Press (2015-02-24 ) By (author) :Khaled Shalaby Ahmed book link: www.morebooks.de/store/gb/book/the-barrier-properties-of-alternative-skin-models-for-human-skin/isbn/978-3-639-51167-3

 

 

  1.  
2017

Department of Pharmaceutics

1. Mohammed Elmowafy, Ahmed Samy, Abdelaziz E. Abdelaziz, Khaled Shalaby, Ayman Salama, Mohamed A. Raslan, and Mohamed A. Abdelgawad. Polymeric nanoparticles based topical gel of poorly soluble drug: Formulation, ex-vivo and in vivo evaluation. Beni-Suef University Journal of Basic and Applied Sciences 6:184-191. 2017.

2. Mohd Qumbar, Ameeduzzafar, Syed Sarim Imam, Javed Ali, Javed Ahmad, and Asgar Ali. Formulation and optimization of lacidipine loaded niosomal gel for transdermal delivery: In-vitro characterization and in-vivo activity. Biomedicine & Pharmacotherapy 93:255-266. 2017.

3. Ameeduzzafar, Syed Sarim Imam, Syed Nasir Abbas Bukhari, and Asgar Ali. Preparation and evaluation of novel chitosan: gelrite ocular system containing besifloxacin for topical treatment of bacterial conjunctivitis: scintigraphy, ocular irritation and retention assessment. Artificial Cells, Nanomedicine, and Biotechnology:1-9. 2017.

4. Kizilbash N, Khan TA, Khan SS, Meer F (2017) Genetic Basis of Autism Spectrum Disorder. MOJ Cell Sci Rep 4(2): 00085. DOI: 10.15406/mojcsr.2017.04.00085

5. Kamrun Nahar, Md Kamal Hossain and Tanveer Ahmed Khan. Alginate and Its Versatile Application in Drug Delivery. J. Pharm. Sci. & Res. Vol. 9(5), 2017, 606-617.

 Department of Pharmaceutical Chemistry

1. Khaled R. A. Abdellatif, Eman K. A. Abdelall, Mohamed A. Abdelgawad, Dina M. E. Amin, and Hany A. Omar. Design, synthesis and biological evaluation of new 4-(4-substituted-anilino)quinoline derivatives as anticancer agents. Medicinal Chemistry Research 26:929-939. 2017.

2. Amany Belal, and Mohamed A. Abdelgawad. New benzothiazole/benzoxazole-pyrazole hybrids with potential as COX inhibitors: design, synthesis and anticancer activity evaluation. Research on Chemical Intermediates 43:3859-3872. 2017.

3. Mohamed A. Abdelgawad, Madlen B. Labib, and Mahmoud Abdel-Latif. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study. Bioorganic Chemistry 74:212-220. 2017.

4. K. R. A. Abdellatif, M. A. Abdelgawad, M. B. Labib, and T. H. Zidan. Synthesis and Biological Evaluation of New Diarylpyrazole and Triarylimidazoline Derivatives as Selective COX-2 Inhibitors. Arch Pharm (Weinheim) 350. 2017.

5. M. A. Abdelgawad, R. B. Bakr, and H. A. Omar. Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents. Bioorg Chem 74:82-90. 2017.

6. S. S. Alsayed, H. A. Elshemy, M. A. Abdelgawad, M. S. Abdel-Latif, and K. R. Abdellatif. Design, synthesis and biological screening of some novel celecoxib and etoricoxib analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile. Bioorg Chem 70:173-183. 2017.

7. R. A. Abdellatif Khaled, A. Abdelgawad Mohamed, A. H. Elshemy Heba, M. Kahk Nesma, and M. El Amir Dalia. Design, Synthesis, Antioxidant and Anticancer Activity of New Coumarin Derivatives Linked with Thiazole, Isoxazole or Pyrazole Moiety. Letters in Drug Design & Discovery 14:773-781. 2017.

8. Mostafa H. Abdelrahman, Bahaa G. M. Youssif, Mohamed A. abdelgawad, Ahmed H. Abdelazeem, Hussein M. Ibrahim, Abd El Ghany A. Moustafa, Laurent Treamblu, and Syed Nasir Abbas Bukhari. Synthesis, biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory activity. European Journal of Medicinal Chemistry 127:972-985. 2017.

9. Mohamed A Abdelgawad, Rania B Bakr, Ahmed O El-Gendy, Gehan M Kamel, Amany A Azouz & Syed Nasir Abbas Bukhari .Discovery of a COX-2 selective inhibitor hit with anti-inflammatory activity and gastric ulcer protective effect. Future Medicinal Chemistry. Published Online: 27 Oct 2017  https://doi.org/10.4155/fmc-2017-0115.

10. Noreen Sobia, Arshad Mahira, Ghumman Shazia Akram, Noureen Shazia, Malik Muhammad Zubair, and Syed Nasir Abbas Bukhari. Smart Gel System of Linum usitatissimum Mucilage as Vehicle of Ophthalmic Drug: in vitro and in vivo Study. Bioinspired, Biomimetic and Nanobiomaterials 0:1-35. https://doi.org/10.1680/jbibn.17.00019

11. Gulzar Muhammad, Muhammad Ajaz Hussain, Muhammad Amin, Syed Zajif Hussain, Irshad Hussain, Syed Nasir Abbas Bukhari, and Muhammad Naeem-ul-Hassan. Glucuronoxylan-mediated silver nanoparticles: green synthesis, antimicrobial and wound healing applications. RSC Advances 7:42900-42908. 2017.

12. L. Jalili-Baleh, H. Nadri, A. Moradi, Syed Nasir Abbas Bukhari, M. Shakibaie, M. Jafari, M. Golshani, F. Homayouni Moghadam, L. Firoozpour, A. Asadipour, S. Emami, M. Khoobi, and A. Foroumadi. New racemic annulated pyrazolo[1,2-b]phthalazines as tacrine-like AChE inhibitors with potential use in Alzheimer's disease. Eur J Med Chem 139:280-289. 2017.

13. M. A. Haque, I. Jantan, and Syed Nasir Abbas Bukhari. Tinospora species: An overview of their modulating effects on the immune system. J Ethnopharmacol 207:67-85. 2017.

14. Syed Nasir Abbas Bukhari, G. B. Kumar, H. M. Revankar, and H. L. Qin. Development of combretastatins as potent tubulin polymerization inhibitors. Bioorg Chem 72:130-147. 2017.

15. H. M. Revankar, Syed Nasir Abbas Bukhari, G. B. Kumar, and H. L. Qin. Coumarins scaffolds as COX inhibitors. Bioorg Chem 71:146-159. 2017.

16. G. F. Zha, H. L. Qin, B. G. M. Youssif, M. W. Amjad, M. A. G. Raja, A. H. Abdelazeem, and Syed Nasir Abbas Bukhari. Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance. Eur J Med Chem 135:34-48. 2017.

17. Muhammad Tahir Haseeb, Muhammad Ajaz Hussain, Khawar Abbas, Bahaa G. M. Youssif, Sajid Bashir, Soon Hong Yuk, and Syed Nasir Abbas Bukhari. Linseed hydrogel-mediated green synthesis of silver nanoparticles for antimicrobial and wound-dressing applications. International Journal of Nanomedicine 12:2845-2855. 2017.

18. H. L. Qin, J. Leng, B. G. M. Youssif, M. W. Amjad, M. A. G. Raja, M. A. Hussain, Z. Hussain, S. N. Kazmi, and Syed Nasir Abbas Bukhari. Synthesis and mechanistic studies of curcumin analog-based oximes as potential anticancer agents. Chem Biol Drug Des 90:443-449. 2017.

19. Hany A. El-Sherief, Gamal El-Din A. Abuo-Rahma, Mai E. Shoman, Eman A. Beshr, and Rehab M. Abdel-baky. Design and synthesis of new coumarin–chalcone/NO hybrids of potential biological activity. Medicinal Chemistry Research. 2017. https://doi.org/10.1007/s00044-017-2004-9

20. Mohammed Gamal, Ali Turki, Almonzer Al-Shemari, Abd Alla Alomari. Comparative Study for Selection of the Optimum Mobile Phase for Separation of Caffeine and Paracetamol by Using TLC Chromatographic Method. International journal of pharmaceutical quality assurance. doi.org/10.25258/ijpqa.v8i1.8437

21. Mohammed Gamal, Nouruddin W. Ali, Mohammed R. Elghobashy and Mohammed Abdelkawy. Simultaneous Determination of Ternary Mixture of Aspirin, Caffeine and Orphenadrine Citrate by Simple RP-TLC Spectrodensitometric Method. British Journal of Pharmaceutical Research, ISSN: 2231-2919,Vol.: 14, Issue.: 4 Page 1-11   DOI : 10.9734/BJPR/2016/31194

22. Morouj Ibrahim Sallam, Zelal Talha Abdulmajid, Amal Mohammed Alamri, Mohammed Gamal, and Ahmed M. Gouda. Prevalence  of  Vitamin  D  deficiency  and  community  awareness  among  women's in Jeddah. Scholars Report2017 may; 2(1): 46-55.

23. Bamofleh EA, Mohammed JA , Abdelrahim MEA, and Gamal M. The Reasons Behind Prevalence of Captagon Addiction in Jeddah and Community Awareness: A Questionnaire-Based Study. ScholReps 2017 April; 2(1)

24. R. B. Bakr, A. B. M. Mehany, and K. R. A. Abdellatif. Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives. Anticancer Agents Med Chem 17:1389-1400. 2017.

25. M. H. Abdelrahman, A. S. Aboraia, B. G. M. Youssif, and B. E. M. Elsadek. Design, synthesis and pharmacophoric model building of new 3-alkoxymethyl/3-phenyl indole-2-carboxamides with potential antiproliferative activity. Chem Biol Drug Des 90:64-82. 2017.

26. H. H. Abdu-Allah, B. G. Youssif, M. H. Abdelrahman, M. K. Abdel-Hamid, R. S. Reshma, P. Yogeeswari, T. Aboul-Fadl, and D. Sriram. Synthesis and anti-mycobacterial activity of 4-(4-phenyl-1H-1,2,3-triazol-1-yl)salicylhydrazones: revitalizing an old drug. Arch Pharm Res 40:168-179. 2017.

27. A. H. Abdelazeem, M. T. El-Saadi, E. G. Said, B. G. M. Youssif, H. A. Omar, and S. M. El-Moghazy. Novel diphenylthiazole derivatives with multi-target mechanism: Synthesis, docking study, anticancer and anti-inflammatory activities. Bioorg Chem 75:127-138. 2017.

 Department of Pharmacology

1. M. S. Ali khan, s. Nazan, and a. M. Mat jais. Flavonoids and anti-oxidant activity mediated gastroprotective action of leathery murdah, terminalia coriacea (roxb.) Wight & arn. Leaf methanolic extract in rats. Arq gastroenterol 54:183-191. 2017.

2. M. Afzal, I. Kazmi, R. Khan, P. Rana, V. Kumar, F. A. Al-Abbasi, M. A. Zamzami, and F. Anwar. Thiamine potentiates chemoprotective effects of ibuprofen in DEN induced hepatic cancer via alteration of oxidative stress and inflammatory mechanism. Arch Biochem Biophys 623-624:58-63. 2017.

3. I. Kazmi, S. Saleem, T. Ahmad, M. Afzal, F. A. Al-Abbasi, V. Kumar, and F. Anwar. Protective effect of oleane-12-en-3beta-ol-28-oic acid 3beta-D-glucopyranoside in ethanol induced gastric ulcer by enhancing the prostaglandin E2 level. J Ethnopharmacol 211:394-399. 2017.

4.  Rafidah Hanim Mokhtar, Fakhria Al-Joufi, Anil K Saxena, Imad M Al-Ani, Norlelawati A Talib, Norsidah Ku-Zaifah. The Effects of Eurycoma longifolia on Testosterone and Blood Pressure in High-Fat-Fed Animal Model. Journal of Applied Pharmaceutical Science Volume: 7, Issue : 4, April, 2017.DOI: 10.7324/JAPS.2017.70417.

5. Azza A. Ali, Abeer I. Abd El-Fattah, Shaimaa S. Hussein, Hanan A. Abd El-Samea, Karema Abu-Elfotuh. The Potential Role of Some Nutrients and Drugs in Providing Protection from Neurotoxicity Induced by Aluminium in Rats. International Journal of Environmental and Ecological Engineering 2017; 4: 1.

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